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[EN] The use of a DNA sequence encoding a 1-deoxy-D-xylulose-5-phosphate synthase (DOXS) to produce plants with an increased tocopherol vitamin K chlorophyll and/or carotenoid content is new. Independent claims are also included for the following: (1) a m
Industry:
Pharma
Inventor:
HERBERS KARIN (DE); EBNETH MARCUS (DE); REINDL ANDREAS (DE); LEON MEJIA PATRICIA (--); ESTEVES PALMAS JUAN MANUEL (--); CANTERO GRACIA MARIA ARACELI (--)
[EN] A process is taught for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G using a Penicillium chrysogenum transformant strain expressing expandase. \
Industry:
Pharma
Inventor:
BOVENBERG ROELOF ARY LANS (NL); KOEKMAN BERTUS PIETER (NL); SCHIPPER DIRK (NL); Vollebregt Adrianus Wilhelmus Hermanus (NL)
[EN] Recombinant organisms are provided comprising genes encoding genes encoding glycerol dehydratase 13-propanediol oxidoreductase a gene encoding vitamin B12 receptor precursor (BtuB) a gene encoding vitamin B12 transport system permease protein (BtuC)
Industry:
Chemical
Inventor:
TRIMBUR DONALD E (US); WHITED GREGORY M (US); GATENBY ANTHONY A (US); BULTHUIS BEN (NL)
[EN] This invention relates to the genetic modification of a microbe to enhance its production of an enzyme beta-glucosidase that is important in the cellulose conversion process. The inventors have discovered genetic constructs that when expressed in rec
Industry:
Energy
Inventor:
WHITE THERESA C (--); HINDLE CHRISTOPHER D (--)
The complete sequence of the gene cluster for the monensin type I polyketide synthase, from S. cinnamonensis, is provided. Thus variant polyketides containing monensin-derived elements can be genetically engineered. Furthermore there are features, e.g. a
Industry:
Pharma
Inventor:
None (--)
[EN] Method for removing DNA molecules containing one or more polymerase-generated mutations in a population of enzymatically amplified DNA duplexes comprising the steps of denaturing and reannealing the population of DNA duplexes contacting the reanne
Industry:
General
Inventor:
Modrich Paul L. (US)
[EN] A system and method for simulating the operation of biochemical networks includes a computer having a computer memory used to store a set of objects each object representing a biochemical mechanism in the biochemical network to be simulated. Most
Industry:
General
Inventor:
McAdams Harley H. (US)
[EN] The present invention relates generally to the fields of oligonucleotide synthesis. More particularly it concerns the assembly of genes and genomes of completely synthetic artificial organisms. Thus the present invention outlines a novel approach to
Industry:
General
Inventor:
EVANS GLEN A (US)
[EN] The invention concerns making and evaluating synthetic regulatory regions for controlling gene expression. The invention features a method for identifying transcription factor binding sites and a method for evaluating the regulatory functions of synt
Industry:
General
Inventor:
SCHWARTZ ROBERT J (US); EASTMAN ERIC M (US); NORDSTROM JEFF (US); LI XUYANG (US)
[EN] The present invention provides genetically altered plants and plant cells that have been modified to contain expression system(s) capable of expressing a functional polyketide synthase (PKS). The present invention further provides methods of producin
Industry:
Pharma
Inventor:
BETLACH MARY C (--)
Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nuclei
Industry:
Pharma
Inventor:
None (--)
A polyketide synthase (“PKS”) of Type I is a complex multienzyme including a loading domain linked to a multiplicity of extension domains. The first extension module receives an acyl starter unit from the loading domain and each extension modu
Industry:
Pharma
Inventor:
None (--)
[EN] Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of
Industry:
Pharma
Inventor:
SANTI DANIEL V (--); BARR PHILIP J (--); ASHLEY GARY W (--)
[EN] The present invention provides an improved method for the production of 13-propanediol from a variety of carbon sources is an organism comprising DNA encoding protein X of a dehydratase or protein X in combination with at least one of protein 1 prote
Industry:
Chemical
Inventor:
DUNN-COLEMAN NIGEL S (US); DIAZ-TORRES MARIA (US); CHASE MATTHEW W (US); TRIMBUR DONALD (US)
[EN] Recombinant organisms are provided comprising genes encoding a glycerol-3-phosphate dehydrogenase and/or a glycerol-3-phosphatase activity useful for the production of glycerol from a variety of carbon substrates.\[FR] Cette invention concerne des or
Industry:
Chemical
Inventor:
HSU AMY KUANG-HUA (US); LAREAU RICHARD D (US); HAYNIE SHARON LORETTA (US); GATENBY ANTHONY ARTHUR (US); BULTHUIS BEN A (NL)
[EN] The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides and methods for generating and applying libraries of these DNA sequences. In particular the invention relates to the p
Industry:
Pharma
Inventor:
KNAPPIK ACHIM (DE); PACK PETER (DE); GE LIMING (DE); MORONEY SIMON (DE); PLUECKTHUN ANDREAS (CH); ILAG VIC (DE)
A process is provided for the bioconversion of a carbon substrate to 1,3-propanediol by a single organism utilizing microorganisms containing the genes encoding for an active glycerol or diol dehydratase enzyme by contacting these organisms with a carbon
Industry:
Chemical
Inventor:
ANNE LAFFEND LISA (US); VASANTHA NAGARAJAN (US); CHARLES NAKAMURA (US)
The rapamycin gene cluster is an example of a gene cluster which includes a gene (rapL) leading to the formation of a precursor compound (pipecolic acid, in this case) which is required for inclusion in the larger product (rapamycin) produced by the enzym
Industry:
Pharma
Inventor:
None (--)
[EN] The disclosure describes a method for incorporating into double stranded DNA and RNA base pairs composed of pairing units that fit the Watson-Crick geometry in that they involve a monocyclic six membered ring pairing with a fused bicyclic heterocycli
Industry:
General
Inventor:
BENNER STEVEN A (CH)
[EN] 2095861 9209695 PCTABS00013 This invention relates to the production of structural proteins by cloning and expressing artificial genes in bacteria. The proteins produced by the instant invention are useful as spinnable fibers.This invention relates t
Industry:
Chemical
Inventor:
HOESS RONALD H (US); O'BRIEN JOHN P (US); SALEMME FRANCIS R (US)