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[EN] Disclosed herein are methods and compositions for genome editing of a Rosa locus using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided as
Industry:
Research
Inventor:
CUI XIAOXIA (US); HOLMES MICHAEL C (US); GREGORY PHILIP D (US); DAVIS GREGORY (US); WEINSTEIN EDWARD J (US)
Industry:
Chemical
Inventor:
BEKKER, Martijn|TEIXEIRA DE MATTOS, Maarten Joost|HELLINGWERF, Klaas Jan
[EN] Compositions and methods for producing fatty acid derivatives using recombinant microorganisms are described herein.\[EN] Compositions and methods for producing fatty acid derivatives using recombinant microorganisms are described herein. \
Industry:
Energy
Inventor:
SCHIRMER ANDREAS W (US); TRINH NA M (US); Schirmer Andreas W. (--); Trinh Na M. (--)
Industry:
Research
Inventor:
ROBERTS, Nicholas, John|KNAPP, Kurtis, Gale
[EN] Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host
Industry:
General
Inventor:
GLASS JOHN I (US); MERRYMAN CHARLES E (US); SMITH HAMILTON O (US); LARTIGUE CAROLE (US); HUTCHISON CLYDE A (US); VASHEE SANJAY (US); BENDERS GWYNEDD A (US); ALGIRE MIKKEL A (US); NOSKOV VLADIMIR N (US); CHUANG RAY-YUAN (US)
Industry:
Life Sciences
Inventor:
KERFELD, Cheryl, A.|KINNEY, James, N.
Some aspects of this invention provide methods and bioreactors for converting a carbon source into a lipid. In some embodiments, lipid production is carried out in an aerobic fermentor and carbon dioxide generated during lipid production is converted into
Industry:
Chemical
Inventor:
Stephanopoulos; Gregory
Described herein are novel biological converter switches that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for converting analog inputs to digital outputs, and digital inputs to analog outputs, i
Industry:
Electronic
Inventor:
COLLINS, James, J.|LU, Timothy Kuan-Ta
[EN] Certain aspects of the present invention provide devices and methods for preparing oligonucleotides and for assembling nucleic acid molecules using microfluidic devices.\[FR] Certains aspects de la présente invention portent sur des dispositifs et de
Industry:
General
Inventor:
CHU LARRY LI-YANG (US)
Industry:
Research
Inventor:
HLUBEK, Andrea|BIESGEN, Christian
Industry:
Research
Inventor:
AJIKUMAR, Parayil, K.|STEPHANOPOULOS, Gregory|PHON, Too, Heng
Industry:
Research
Inventor:
KIM, Hak-Sung|KIM, Jin-Hyun|LEE, Sang-Chul|JEONG, Young-Su
Methods and compositions are provided for manipulating the genome of host cell to produce at least one exogenous gene product. Also provided are methods and composition for producing a programmable cell comprising a plurality of exogenous genes, wherein e
Industry:
Research
Inventor:
JACOBSON, Joseph|CHURCH, George
The present invention provides a novel method of producing a recombinant bacterium for production of a non-natural protein, including: (1) expressing tRNA in a bacterium, which tRNA recognizes UAG codon; (2) expressing an aminoacyl-tRNA synthetase in the
Industry:
Research
Inventor:
YOKOYAMA SHIGEYUKI|MUKAI TAKAHITO|SAKAMOTO KENSAKU|MATSUMOTO AKIKO
The invention described herein presents compositions and methods for a multistep biological and chemical process for the capture and conversion of carbon dioxide and/or other forms of inorganic carbon into organic chemicals including biofuels or other use
Industry:
Chemical
Inventor:
REED JOHN S
The present invention provides for a method of producing a cinnamoyl anthranilate, or analog thereof, in a genetically modified host cell.
Industry:
Chemical
Inventor:
LOQUE DOMINIQUE|EUDES AYMERICK GUILLAUME
A construct containing a gene operably linked to a promoter having activity in cyanobacteria, and vector and cyanobacterium comprising such construct for increasing the yield of fatty alcohols in cyanobacterium is provided.
Industry:
Research
Inventor:
LU XUEFENG|GAO QIANQIAN|WANG WEIHUA|ZHAO HUI
Described are methods and compositions for the detection of target genes. The inventors have developed a synthetic nucleic acid sensor-effector gene circuit. In cells without a target gene, the circuit suppresses e.g., effector production, but in the pres
Industry:
Life Sciences
Inventor:
COLLINS JAMES J|LU TIMOTHY KUAN-TA
The present invention provides for a genetically modified host cell capable of producing 1-deoxyxylulose 5-phosphate or 1-deoxy-D-xylulose 5-phosphate (DXP) (12), and optionally one or more DXP derived compounds, comprising: (a) a mutant RibB, or function
Industry:
Chemical
Inventor:
KIRBY JAMES|FORTMAN JEFFREY L|NISHIMOTO MINOBU|KEASLING JAY D
Methods and systems for producing a biofuel using genetically modified ammonia-oxidizing bacteria (AOB) are disclosed. In some embodiments, the methods include the following: providing an AOB that have been genetically modified to include a particular met
Industry:
Energy
Inventor:
BANTA SCOTT|CHANDRAN KARTIK|WEST ALAN