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Title:
PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS
Number:
WO2012154854A1
Publication Date:
2012-11-15
Location:
USA
Priority Date:
IPC clasifications:
C12N 1/12
Assignee:
AMYRIS, INC.
Inventor:
MEADOWS, Adam
Class / subclass:
Integration and development / Other useful products obtained
Industry:
Chemical
Abstract:

The present disclosure relates to the use of pantothenate compounds as a non-genetic switch for the production of heterologous acetyl-CoA derived (HACD) compounds in microbial host cells. The invention provides genetically modified microorganisms that are more stable when stored and initially cultured under reduced pantothenate concentrations, cell culture media having reduced concentrations of pantothenate compounds, and methods of producing HACD compounds using the cell culture media and the genetically engineered microorganisms of the invention.

Claims:

NA

Patent Family:
US20120288891A1 WO2012154854A1