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Title:
METHODS FOR GENOMIC MODIFICATION
Number:
WO2012149470A1
Publication Date:
2012-11-01
Location:
USA
Priority Date:
IPC clasifications:
C12N 15/81; C12N 15/90
Assignee:
AMYRIS, INC.
Inventor:
SERBER, Zach|HORWITZ, Andrew
Class / subclass:
Enabling Technologies
Industry:
Research
Abstract:

Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain embodiments, the methods comprise contacting the host cell genome with one or more integration polynucleotides comprising an exogenous nucleic acid to be integrated into a genomic target site, and a nuclease capable of causing a double-strand break near or within the genomic target site.

Claims:

NA

Patent Family:
US20120277120A1 WO2012149470A1