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Title:
PRODUCTION OF MEVALONATE, ISOPRENE, AND ISOPRENOIDS USING GENES ENCODING POLYPEPTIDES HAVING THIOLASE, HMG-COA SYNTHASE AND HMG-COA REDUCTASE ENZYMATIC ACTIVITIES
Number:
WO2012149469A1
Publication Date:
2012-11-01
Location:
USA
Priority Date:
IPC clasifications:
C12N 1/21; C12N 9/00; C12N 9/10; C12P 5/00; C12P 7/02; C12P 7/04; C12P 7/42
Assignee:
DANISCO US INC.|THE GOODYEAR TIRE & RUBBER COMPANY
Inventor:
BECK, Zachary, Q.|MILLER, Michael, C.|PERES, Caroline, M.|PRIMAK, Yuliya, A.|PUCCI, Jeff, P.|WELLS, Derek, H.
Class / subclass:
Integration and development / Other useful products obtained
Industry:
Chemical
Abstract:

The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in microorganisms via the heterologous expression of the mvaE and mvaS genes from the organisms Listeria grayi DSM 20601, Enterococcus faecium, Enterococcus gallinarum EG2, and Enterococcus casseliflavus.

Claims:

NA

Patent Family:
US20120276603A1 WO2012149469A1