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Title:
BIOPROCESS AND MICROBE ENGINEERING FOR TOTAL CARBON UTILIZATION IN BIOFUEL PRODUCTION
Number:
US20110177564A1
Publication Date:
2011-07-21
Location:
USA
Priority Date:
IPC clasifications:
C12M 1/00; C12M 1/04; C12P 1/00; C12P 1/02; C12P 1/04; C12P 7/14; C12P 7/64; C12P 19/04
Assignee:
Massachusetts Institute of Technology
Inventor:
Stephanopoulos; Gregory
Class / subclass:
Applied Technologies / Other technologies for the biological synthesis of useful products / Other chemicals (organic acids, vitamins, etc)
Industry:
Chemical
Abstract:

Some aspects of this invention provide methods and bioreactors for converting a carbon source into a lipid. In some embodiments, lipid production is carried out in an aerobic fermentor and carbon dioxide generated during lipid production is converted into a carbon substrate by CO2 fixation in an anaerobic fermentor. In some embodiments, the carbon substrate generated by CO2 fixation is used as the carbon source for lipid production, thus achieving total carbon utilization in lipid production

Claims:

1. A method comprising (a) culturing a first organism in the presence of a carbon source under conditions suitable for the organism to oxidize the carbon source, wherein the organism produces CO2 as part of the oxidation process; and (b) culturing a second organism in the presence of CO2 produced in (a) under conditions suitable for the second organism to reduce the CO2, wherein the organism produces a carbon substrate as part of the reduction process.

Patent Family:
WO2011088364A2 US20110177564A1 WO2011088364A2 WO2011088364A3 WO2011088364C1 WO2011088364C2